URINARY TRACT IMAGINGđź—¸

URINARY TRACT IMAGING

Contrast X-rays

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Dye studies for urethra
Route
IVP
Intravenous Pyelogram
• via IV
• Urethra is not seen
RGP
Retrograde Pyelogram
• from down upwards
• No bladder distension
• view
Ureter/Renal Pelvis
RGU
Retrograde Urethrogram
• Preferred for anterior urethra evaluation for strictures.
• e.g.,
urethral strictures, urethral injury/rupture.
MCU / VCUG
Micturating Cystourethrogram / Voiding cystourethrogram
• 300ml contrast via foleys cannulation
• Distend the bladder with contrast
•
IOC for
1. VUR
2. PUV

Computed Topography (CT) Scans

CT IVP
CT IVP
T2 MR
T2 MR
CT Scans
Identify
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CT-IVU or CT-IVP.
KUB + White bone
Colourful imaging can be produced from urine.
T2 Magnetic Resonance (MR).
KUB
NO White bone
Advantages
1. without contrast → Urine appears white
2.
Safe in renal failure

Urolithiasis

  • The best investigation for Urinary tract calculi is CT since they are calcified.
  • CT Urography (also Radiolucent) >> Non-contrast CT (NCCT)
  • Partial vs complete obstruction: Diuretic DTPA scan

Ureteric calculi

  • Ureteric stone is generally vertically oval.
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Renal Calculus

  • A white area (right kidney) → right renal calculus
    • Right kidney + psoas major muscle located posteromedially.
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  • On ultrasound → echogenic area + shadow behind it.
    • Shadow → posterior acoustic shadowing.
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Vesicle calculus

  • Dense calcification in the center of the pelvis is observed.
  • This is the bladder stone or vesical calculus.
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Hydronephrosis

  • Left kidney
    • gray color density → fluid.
    • Enhancing rim → renal parenchyma.
      • Rim sign seen in hydronephrosis.
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Stag horn calculus

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  • Calcium Ammonium Magnesium Phosphate.
  • Associated with
    • Proteus urinary tract infection.
    • Parathyroid adenoma → Hypercalcemia → Calcium deposits in kidney
  • Radio-opaque.
  • "Coffin Lid" shaped.
  • Formed in alkaline urine.
  • Features
    • Smooth surface, large size.
    • takes up the shape of the pelvis and calyces.
    • Calcification with lobulated appearance, i.e. parenchymal
  • Coffin lu avathirikkan Maaninte (Staghorn) irachi thinnanam + Protein (Proteus) thinnanam→ Strong (Struvite) avanam
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Putty kidney

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  • Cement (amorphous calcification) + lobulated appearance = parenchymal calcification
  • Moth eaten calyces
    • Earliest sign in the IVP for renal TB
    • irregularity of the calyx.
  • Later stages of TB
  • → non-functional kidney and auto-nephrectomy.
  • Sterile pyuria is seen in urinary TB.

Corkscrew and Beaded appearance

  • Multiple ureteric strictures
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Thimble bladder

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  • small, contracted bladder
  • Heal with fibrosis
    • bladder wall calcification

Investigations:

  • Urine examination: Sterile pyuria (pus cells +, culture -).
  • Confirmatory:
    • ZN Staining of centrifuged 3 morning urine samples.

Note:

  • If genital TB
    • Genital swab for polymerase chain reaction (PCR) testing
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B/L Nephrocalcinosis/ Medullary Nephrocalcinosis

  • Lucent areas are observed between opaque areas.
  • 2 causes
    • A/w Hyperparathyroidism
    • Medullary sponge kidney
  • Functional kidney
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Medullary sponge kidney appearance in IVP

  • Paintbrush or bouquet of flowers appearance.
  • Dilated collecting ducts / medullary ducts (Bellini ducts)
  • A/w nephrocalcinosis and recurrent renal stones
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Differentiating Stag Horn Calculus, PUJ Obstruction and VUR

  • DMSA scan for scarring.
Condition
IOC
Features
Stag Horn Calculus
plain x-ray.
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PUJ Obstruction
IVP
Non-visualization of the ureter
hydronephrosis without hydroureter
affected kidney is dilated → hydronephrosis
affected ureter is not seen →
PUJ obstruction
VUR
MCU / VCUG
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Popcorn calcification

  • Popcorn calcification is observed in the pelvis.
  • It is incomplete calcification.
  • In post-menopausal females
    • calcific degeneration of uterine fibroid.
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Pyelonephritis

  • Symptoms include fever, dysuria, and flank pain.

Acute pyelonephritis

  • In acute pyelonephritis, the kidney is enlarged.
  • In chronic pyelonephritis, the kidney is shrunken.
  • Enlarged edematous kidney → Total / Focal
  • A striated appearance is observed.
  • Reduced areas of cortical vascularity on power Doppler
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Emphysematous pyelonephritis

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  • Black areas
    • Air is contained within the kidney and surrounding it.
  • Organism: E.coli.
    • Note: clostridium → emphysematous cholecystitis
  • Common in immunocompromised, DM patients.
  • Can turn fulminant and septic.
  • IOC: CECT (gas in/around kidney).
  • Management: Antibiotics + drainage.

Tuberculosis (TB) of the Urinary Tract

  • TB causes destruction and fibrosis.
  • The is the moth-eaten calyx.
    • This suggests the
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Putty kidney

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  • Cement (amorphous calcification) + lobulated appearance = parenchymal calcification
  • Moth eaten calyces
    • Earliest sign in the IVP for renal TB
    • irregularity of the calyx.
  • Later stages of TB
  • → non-functional kidney and auto-nephrectomy.
  • Sterile pyuria is seen in urinary TB.

Corkscrew and Beaded appearance

  • Multiple ureteric strictures
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Thimble bladder

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  • small, contracted bladder
  • Heal with fibrosis
    • bladder wall calcification

Investigations:

  • Urine examination: Sterile pyuria (pus cells +, culture -).
  • Confirmatory:
    • ZN Staining of centrifuged 3 morning urine samples.

Note:

  • If genital TB
    • Genital swab for polymerase chain reaction (PCR) testing

Ureter Appearances

Ureterocele:

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  • IVU: "Cobra Head" or "Adder Head" sign.
  • Cystic dilatation of ureteric terminal end.
  • Surgery: Ureter reimplantation.

Duplication or Duplex moiety

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Weigert-Meyer Rule:

  • Upper pole ureter:
    • Ectopic insertion.
    • Inferomedial to normal.
  • Middle/lower pole ureter:
    • Normal insertion.
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Ectopic Sites:

  • Male: Urethra.
  • Female: Vagina (causes urinary dribbling).

Investigation:

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  • Intravenous Urogram (IVU):
    • Urograffin dye used.
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  • "Drooping Lily" sign
    • (duplication + pelvic malrotation).
    • Mnemonic: Droop → Dupe
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Management:

  • Ureter reimplantation.

Medullary sponge kidney appearance in IVP

  • Paintbrush or bouquet of flowers appearance.
  • Dilated collecting ducts / medullary ducts (Bellini ducts)
  • A/w nephrocalcinosis and recurrent renal stones
    • notion image

PCKD (AD) (Autosomal dominant polycystic kidney disease)

  • The renal calyces are separated by the cysts.

Retroperitoneal fibrosis (Ormond's disease)

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  • Can compress ureters → hydronephrosis
  • "Maiden Waist" deformity, medial indrawing of ureters.
  • Causes:
    • Idiopathic
    • post-radiotherapy
    • drug-induced (Methysergide).
  • Management: DJ Stenting.
  • Mnemonic: Purakil ninn (retroperioneal) DJ () kalikkunna Maid () ne Ormayundo (Ormond)

Horseshoe Kidney

  • Known as joining hands or handshake or flower vase appearance
    • Has association with Turner's syndrome.
    • IVU: "Flower Vase" or "Hand Shake" sign.
    • Fuse at isthmus
    • Inferior mesenteric Artery → Anterior to isthmus → Prevent ascent
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        IVU
        IVU

Retrocaval ureter:

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  • Right ureter passes behind IVC.
  • Hydronephrosis + hydroureter (of the proximal ureter)
  • "Reversed J" or "FishHook" sign.

Renal Papillary Necrosis

  • Signet ring appearance.
  • Contrast is seen around the necrosed papilla.
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Bladder Appearances

Christmas or pine or fir tree appearance

  • Seen in neurogenic bladder.
  • The tone of the bladder is affected, causing a shape change from round to elongated.
  • Multiple diverticuli are present.
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Teardrop or pear shape or inverted pear shape appearance

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  • In an IVP image, the bladder appears to have a teardrop shape.
  • A normal bladder is compressed by external forces, causing elongation.
  • Causes include:
    • Extrinsic compression of the bladder.
    • Any pelvic cause.
      • e.g., pelvic lipomatosis, pelvic abscess, pelvic hematoma, pelvic lymphadenopathy, pelvic vessel aneurysm.

Fetal skull calcification of the urinary bladder

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  • Seen in schistosomiasis.
  • Bladder wall calcification
  • Schistosoma haematobium resides in the vesical venous plexus of the bladder.

Imaging in PUV

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  • USG
    • "Keyhole sign"
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  • MCU → IOC
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  • Management: Fulguration of the valve.

Urethral Pathology

Urethral rupture

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Anterior Urethral Injury
Posterior Urethral Injury
Injured Part
• Penile/bulbar urethra
• Membranous/ prostatic urethra
Mode of Injury
• Direct trauma/straddle injury
• Secondary to pelvic fracture
Features
• Superficial perineal hematoma
•
around penis/scrotum
• Deep perineal hematoma,
•
Vermooten sign (Floating prostate)
  • Contrast flows out of the urethra.
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Bladder Rupture

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Type
Extraperitoneal rupture
Intraperitoneal rupture
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(more common)
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Sign
molar tooth sign.
Contrast in paracolic gutters and inter-bowel loops area
Secondary to
pelvic fracture.
blunt/penetrating trauma to a full bladder.
Associated with
deep perineal hematoma.
peritonitis, syncopal attack.
Management
Foley’s/Suprapubic Catheter
(SPC) for 7 days.
Laparotomy +
Bladder repair in 2 layers +
Foley’s/SPC.

Renal Mass

Differentiating renal mass in an adult on CT

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  • Macroscopic fat indicates Angiomyolipoma.
  • No fat and no enhancement indicates Cyst.
  • No fat with enhancement indicates Renal cell carcinoma or other.

Renal cyst

Angiomyolipoma

  • Features:
    • Type of Hamartoma
    • Benign,
    • common in 5th-6th decade,
    • origin from perivascular epitheloid cells (EPC).
    • Neovascular tumor
    • Only condition where fat is seen in kidney
    • A/w Tuberous sclerosis complex (TSC).
  • Clinical Features:
    • Usually asymptomatic.

CECT (IOC)

  • Fat → looks dirty black on CT.
  • B/L angiomyolipomas
    • A/w tuberous sclerosis.
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Renal cell carcinoma

  • CECT (IOC).
    • Solid enhancing lesion.
    • Clear cell carcinoma is the most common.
    • It is hyper-enhancing.
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Renal Cystic Lesions

  • Includes:
    • Autosomal dominant polycystic kidney disease (ADPKD).
    • Autosomal recessive polycystic kidney disease (ARPKD).
    • Multicystic dysplastic kidney.

Xray

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ADPKD

  • On CT scan (Image 1), white bone is observed.
    • Both kidneys are enlarged in size and have multiple cysts.
  • On MRI (Image 2), black bone is observed.
    • Both enlarged kidneys have multiple cysts.
  • In IVP, initial or nephrogram phase:
    • Multiple cysts do not take up the contrast,
    • forming filling defects in the kidney.
  • Spider leg appearance.
    • d/t Splayed collecting system
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  • Swiss cheese appearance
    • On nephrogram
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ARPKD

  • Striated appearance or sunray appearance of the kidneys.
  • The kidney appears echogenic on ultrasonography.

Renal Vascular Pathology

Renal artery stenosis

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  • Affects the ostium.
  • Young patient (without a family history of hypertension)
  • 1st investigation is renal Doppler (Image 1)
    • has a slow and blunted uptake.
      • i.e. pulsus parvus et tardus waveform (Image 2)
    • Normal renal artery has a quick upstroke.
  • 2nd investigation is CT-angiography or MR-angiography.
  • Gold standard procedure is digital subtraction angiography (DSA).

Fibromuscular dysplasia

  • Beaded appearance.
  • Seen in an MR-angiography.
  • Indicates multiple strictures in the renal artery.
  • Common in young adult females.
  • Also presents with hypertension (similar to renal artery stenosis).
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Adrenal Lesions

  • In CT scans, the adrenal gland is seen as an inverted Y-shape or V-shape.
  • On the right side, it lies behind the inferior vena cava.

Adrenal adenoma

  • The most common incidental adrenal lesion detected.
  • Features:
    • Fat-containing.
    • Rapid wash-in and rapid wash-out of the contrast.
  • Hounsfield unit (HU)
    • Negative or <10 is considered → adrenal adenoma.
    • If > 10 → take a delayed scan → shows ↑sed washout, s/o
      • Low lipid Adrenal adenoma
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Pheochromocytoma

  • Lightbulb sign on T2 weighted MRI (T2W MRI).
  • hyperintense in T2ZW MRI
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  • BIOPSY/FNAC → Contraindicated
Category
Investigation
Notes
Screening Test/
Initial
24-hour urine fractionated metanephrine.
>>
24 hr urine VMA
Sensitivity and specificity: 98%.
Confirm → IOC/
Best investigation
Serum plasma free metanephrines
Most sensitive test
100% sensitivity.
Best / Radiological IOC
MRI abdomen.
Shows light bulb sign
IOC for Extra-adrenal Pheo
Gallium dotatate (DOTANOC) PET scan scan → detect somatostatin receptors /

Tc 99 Dopa PET
Best for detecting metastasis/extra-adrenal sites
FOR METS
(Nucleotide scan) Metaiodobenzylguanidine
(MIBG) scintigraphy
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Localise
Extra adrenal Pheo
or mets
Radeon
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